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What if cancer comes back?

Definition

One of the most common fears for people who have had cancer is that it may return after initial treatment. When cancer comes back, it is called a recurrence. Cancer can recur in the same spot or in a whole different area of your body. No one likes to think about having cancer again, but it is important to learn about recurrence so you can move on with your life despite the uncertainty.

Why Cancer Comes Back

Cancer can come back if any cancer cells are left behind after treatment. This does not mean that your health care team did anything wrong. Sometimes, these cancer cells can't be found by tests. But over time, they grow until they are large enough to be detected. Sometimes, the cancer grows in the same area, but it can also spread to other parts of your body.

There are three types of recurrence:

Understanding Your Risk

This risk of cancer recurring is different for each person. Your own risk depends on several factors:

To learn more about your own risk, talk with your provider. They may be able to give you some idea of your personal recurrence and any signs to watch for.

What You Can Do

While there is nothing you can do to make sure your cancer will not return, there are some steps you can take to try to stay as upbeat and healthy as possible.

What if Your Cancer Does Come Back?

If you do get another cancer diagnosis, it is normal to feel anger, shock, fear, or denial. Facing cancer again is not easy. But you have been through it before, so you have experience in fighting cancer.

Here are some things you can do:

References

Friedman DL. Second malignant neoplasms. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 50.

National Cancer Institute website. Tumor grade. www.cancer.gov/about-cancer/diagnosis-staging/diagnosis/tumor-grade. Updated August 1, 2022. Accessed September 16, 2024.

National Cancer Institute website. Recurrent cancer: when cancer comes back. www.cancer.gov/types/recurrent-cancer. Updated April 2, 2025. Accessed April 29, 2025.

Rock CL, Thomson CA, Sullivan KR, et al. American Cancer Society nutrition and physical activity guideline for cancer survivors. CA Cancer J Clin. 2022;72(3):230-262. PMID: 35294043 pubmed.ncbi.nlm.nih.gov/35294043/.

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Contact Atlanta Obsetrics and Gynaecology at The Womens Center Millennium Hospital - 404-ATL-BABY

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Review Date: 9/6/2024

Reviewed By: Warren Brenner, MD, Oncologist, Lynn Cancer Institute, Boca Raton, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.