Medical marijuana
Marijuana is best known as a drug that people smoke or eat to get high. It is derived from the plant Cannabis sativa. Medical marijuana refers to using marijuana to treat certain medical conditions.
Drug that people smoke or eat to get hi...
Marijuana comes from a plant called hemp. Its scientific name is Cannabis sativa. The main active ingredient in marijuana is THC (short for delta-9...
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Possession of marijuana is illegal under federal law. In the United States, however, over one half of the states have legalized marijuana for medical use.
How Does Medical Marijuana Work?
Medical marijuana may be:
- Smoked
- Vaporized
- Orally consumed (capsules, edibles, tinctures)
- Placed under the tongue (sublingual)
- Place on the mucous membranes of the mouth
- Used topically
- Used rectally as a suppository
Marijuana leaves and buds contain substances called cannabinoids. THC is a cannabinoid that can affect the brain and change your mood or consciousness.
Different varieties of marijuana contain different amounts of cannabinoids. This sometimes makes the effects of medical marijuana hard to predict or control. The effects also may differ depending on how it is taken.
What Conditions Can It Help?
Medical marijuana may be used to:
- Ease pain. This includes different types of chronic pain, including pain from nerve damage.
- Control nausea and vomiting. The most common use is for nausea and vomiting caused by chemotherapy for cancer.
- Make a person feel like eating. This helps people who do not eat enough and lose weight due to other illnesses, such as HIV/AIDS and cancer.
Some small studies show that marijuana might relieve symptoms in people who have:
- Multiple sclerosis
- Crohn disease
- Inflammatory bowel disease
- Epilepsy
Smoking marijuana lowers pressure inside the eyes. But the effect does not last long and this is not often the recommended treatment for glaucoma. Other glaucoma medicines work better to treat the disease.
How Do People Get Medical Marijuana?
In states where medical marijuana is legal, you need a written statement from your health care provider to get the medicine. It must explain that you need it to treat a medical condition or to ease side effects. Your name will be put on a list that lets you buy marijuana from an authorized seller.
What Medical Conditions Qualify?
You can only get medical marijuana if you have certain conditions. The conditions marijuana can be used to treat vary from state to state. The most common ones include:
- Cancer
- HIV/AIDS
HIV/AIDS
Human immunodeficiency virus (HIV) is the virus that causes acquired immunodeficiency syndrome (AIDS). When a person becomes infected with HIV, the ...
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Seizures
A seizure is the physical changes in behavior that occurs during an episode of specific types of abnormal electrical activity in the brain. The term ...
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- Severe chronic pain
- Severe nausea
- Extreme weight loss and weakness (wasting syndrome)
- Severe muscle spasms
- Multiple sclerosis
Side Effects
Possible physical symptoms from using marijuana include:
- A fast or irregular heartbeat
A fast or irregular heartbeat
Palpitations are feelings or sensations that your heart is pounding or racing. They can be felt in your chest, throat, or neck. You may:Have an unpl...
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Dizziness
Dizziness is a term that is often used to describe 2 different symptoms: lightheadedness and vertigo. Lightheadedness is a feeling that you might fai...
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- Drowsiness
Possible mental or emotional side effects include:
- A strong feeling of happiness or well-being
- Short-term memory loss
- Trouble concentrating
- Confusion
Confusion
Confusion is the inability to think as clearly or quickly as you normally do. You may feel disoriented and have difficulty paying attention, remembe...
Read Article Now Book Mark Article - Decreased or increased anxiety
Who Should Not Use Medical Marijuana?
Providers are not allowed to prescribe medical marijuana to people younger than age 18. Other people who should not use medical marijuana include:
- People with heart disease. Some studies have linked marijuana use with increased risk of heart attack and stroke.
- Pregnant women.
- People with a history of psychosis.
Other concerns linked to marijuana use include:
- Dangerous driving or other risky behaviors
- Lung irritation
- Dependence or addiction to marijuana
Prescription Drugs Based on Marijuana Compounds
The US Food and Drug Administration (FDA) has not approved marijuana for treating any health conditions.
However, the FDA has approved two prescription medicines that contain man-made cannabinoids.
- Dronabinol (Marinol). This medicine treats nausea and vomiting caused by chemotherapy and loss of appetite and weight loss in people with HIV/AIDS.
- Nabilone (Cesamet). This medicine treats nausea and vomiting caused by chemotherapy in people who have not had relief from other treatments.
Unlike medical marijuana, the active ingredient in these medicines can be controlled, so you always know how much you get in a dose.
Reviewed By
Laura J. Martin, MD, MPH, ABIM Board Certified in Internal Medicine and Hospice and Palliative Medicine, Atlanta, GA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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Gonzalez D, McCammon SD. Integrating palliative and curative care strategies in the practice of otolaryngology. In: Francis HW, Haughey BH, Hillel AT, et al, eds. Cummings Otolaryngology: Head & Neck Surgery. 8th ed. Philadelphia, PA: Elsevier; 2026:chap 80.
Mostoufi SA. Chronic pain syndrome. In: Frontera WR, Silver JK, Rizzo TD Jr, eds. Essentials of Physical Medicine and Rehabilitation: Musculoskeletal Disorders, Pain, and Rehabilitation. 4th ed. Philadelphia, PA: Elsevier; 2019:chap 98.
National Cancer Institute website. Cannabis and cannabinoids (PDQ) - health professional version. www.cancer.gov/about-cancer/treatment/cam/hp/cannabis-pdq#section/all. Updated May 13, 2025. Accessed December 12, 2025.
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