Colon cancer screening
Colon cancer screening can detect polyps and early cancers in the large intestine. This type of screening can find problems that can be treated before cancer develops or spreads. Regular screenings may reduce the risk for death and complications caused by colorectal cancer.
Colon cancer
Colorectal cancer is cancer that starts in the large intestine (colon) or the rectum (end of the colon). It is also sometimes simply called colon ca...

Polyps
A colorectal polyp is a growth on the lining of the colon or rectum.

Information
SCREENING TESTS
There are several ways to screen for colon cancer.
Stool test:
- Polyps in the colon and small cancers can cause small amounts of bleeding that cannot be seen with the naked eye. But blood can often be found in the stool.
- This method checks your stool for blood.
- A common test used is the fecal immunochemical test (FIT). The fecal occult blood test (gFOBT) was commonly used in the past. Another stool test, commonly known as Cologuard checks for both blood and abnormal stool DNA (sDNA).
Fecal occult blood test
The stool guaiac test looks for hidden (occult) blood in a stool sample. It can find blood even if you cannot see it yourself. It is a common type ...
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Sigmoidoscopy:
- This test uses a small flexible scope to view the lower part of your colon. Because the test only looks at the last one third of the large intestine (colon), it may miss some cancers or polyps that are higher in the large intestine.
- Sigmoidoscopy and a stool test may be used together.
Sigmoidoscopy
Sigmoidoscopy using a flexible scope is a procedure used to see inside the sigmoid colon and rectum. The sigmoid colon is the area of the large inte...
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Colonoscopy:
- A colonoscopy is similar to a sigmoidoscopy, but the entire colon can be viewed.
Colonoscopy
A colonoscopy is an exam that views the inside of the colon (large intestine) and rectum, using a tool called a colonoscope. The colonoscope has a sm...
ImageRead Article Now Book Mark Article - Your health care provider will give you the steps for cleansing your bowel. This is called bowel preparation.
- During a colonoscopy, you receive medicine to make you relaxed and sleepy.
- Sometimes, CT scans are used as an alternative to a regular colonoscopy. This is called a virtual colonoscopy (or CT colography).
Virtual colonoscopy
A virtual colonoscopy (VC) is an imaging or x-ray test that looks for cancer, polyps, or other disease in the large intestine (colon). The medical n...
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Colonoscopy
There are 3 basic tests for colon cancer; a stool test (to check for blood), sigmoidoscopy (inspection of the lower colon), and colonoscopy (inspection of the entire colon). All 3 are effective in catching cancers in the early stages, when treatment is most beneficial.
Other test:
- Capsule endoscopy involves swallowing a small, pill-sized camera that takes a video of the inside of your large intestine. The method is being studied, but it is not recommended for standard screening at this time.

Capsule endoscopy
Capsule endoscopy is a test procedure in which a camera inside a small capsule takes pictures of the lining of your digestive system. The capsule is about the size of a large vitamin pill. After swallowing it, the capsule travels the length of your digestive system and transmits images to a wearable recorder.
SCREENING FOR AVERAGE-RISK PEOPLE
There is not enough evidence to say that any one screening method is best. Colonoscopy is the most thorough but also has the highest risk. Talk to your provider about which test is right for you.
All adults should have a colon cancer screening test starting at age 45.
The most commonly recommended screening options for people with an average risk for colon cancer:
- Colonoscopy every 10 years starting at age 45
- FIT every year (colonoscopy is needed if results are positive)
- Flexible sigmoidoscopy every 5 years or every 10 years plus stool testing with FIT done every year
Other screening options include the following. If any of these tests are positive, colonoscopy is recommended:
- sDNA-FIT every 3 years
- CT colonography (virtual colonoscopy) every 5 years
SCREENING FOR HIGHER-RISK PEOPLE
People with certain risk factors for colon cancer may need earlier (before age 45) or more frequent testing.
More common risk factors are:
- A family history of inherited colorectal cancer syndromes, such as familial adenomatous polyposis (FAP) or hereditary nonpolyposis colorectal cancer (HNPCC).
- A strong family history of colorectal cancer or advanced adenomatous polyps. This usually means close relatives (parent, sibling, or child) who developed these conditions younger than age 60.
- A personal history of colorectal cancer or polyps.
- A personal history of long-term (chronic) inflammatory bowel disease (for example, ulcerative colitis or Crohn disease).
Screening for these groups is more likely to be done using colonoscopy.
Reviewed By
Jenifer K. Lehrer, MD, Gastroenterologist, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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