Allergen

Positive reaction to allergen

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Definition

An allergen is a substance that can cause an allergic reaction. In some people, the immune system recognizes allergens as foreign or dangerous. As a result, the immune system reacts by making a type of antibody called immunoglobulin E (IgE) to defend against the allergen. This reaction leads to allergy symptoms.

Information

Common allergens include:

  • Animal proteins and animal dander
  • Dust
  • Foods (such as egg, peanut, milk, nuts, soy, fish, animal meat, and wheat)
  • Fungal spores
  • Insect and mite feces
  • Insect bites and stings (their venom)
  • Medicines (such as antibiotics or medicines you put on your skin)
  • Natural latex rubber
  • Pollen

References

Custovic A, Tovey E. Allergen control for prevention and management of allergic diseases. In: Burks AW, Holgate ST, O'Hehir RE, et al, eds. Middleton's Allergy: Principles and Practice. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 84.

Stewart GA, Robinson C. The structure and function of allergens. In: Burks AW, Holgate ST, O'Hehir RE, et al, eds. Middleton's Allergy: Principles and Practice. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 26.

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Review Date: 1/1/2025

Reviewed By: Linda J. Vorvick, MD, Clinical Professor Emeritus, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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