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Normal Pregnancy

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What to expect during pregnancy

Aches and pains during pregnancy Choosing the right practitioner Common symptoms during pregnancy Hyperemesis Gravidarum Morning sickness Pregnancy and travel Pregnancy and work Problems sleeping during pregnancy Skin and hair changes during pregnancy Teenage pregnancy

Preparing to go home with your baby

Cribs and crib safety Eat right during pregnancy Preparing your other children

Visits and Tests

Amniocentesis Chorionic villus sampling Genetic counseling before pregnancy Glucose tolerance test-pregnancy Monitoring your baby before labor Nuchal translucency Prenatal care in your first trimester Prenatal care in your second trimester Prenatal care in your third trimester

Macroglossia

Definition

Macroglossia is a disorder in which the tongue is larger than normal.

Information

Macroglossia is most often caused by an increase in the amount of tissue in the tongue, rather than by a growth, such as a tumor.

This condition can be seen in certain inherited or congenital (existing at birth) disorders, including:

• Acromegaly (buildup of too much growth hormone in the body)

• Beckwith-Wiedemann syndrome (growth disorder that causes large body size, large organs, and other symptoms)

• Congenital hypothyroidism (decreased production of thyroid hormone)

• Diabetes (high blood sugar caused by body producing too little or no insulin)

• Down syndrome (extra copy of chromosome 21, which causes problems with physical and intellectual functioning)

• Lymphangioma or hemangioma (malformations in the lymph system or buildup of blood vessels in the skin or internal organs)

• Mucopolysaccharidoses (a group of diseases that cause large amounts of sugar to build up in the body's cells and tissues)

• Primary amyloidosis (a buildup of abnormal proteins in the body's tissues and organs)

References

Alwani MM, Makki FM, Robbins KT. Physiology of the oral cavity. In: Flint PW, Francis HW, Haughey BH, et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 86.

Jones KL, Jones MC, del Campo M. Early overgrowth with associated defects. In: Jones KL, Jones MC, del Campo M, eds. Smith's Recognizable Patterns of Human Malformation. 8th ed. Philadelphia, PA: Elsevier; 2022: F, 198-225.

Rose E. Pediatric upper airway obstruction and infections. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 162.

Review Date: 4/5/2025

Reviewed By: Charles I. Schwartz, MD, FAAP, Clinical Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, General Pediatrician at PennCare for Kids, Phoenixville, PA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.