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Normal Pregnancy

Staying Healthy

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What to expect during pregnancy

Aches and pains during pregnancy Choosing the right practitioner Common symptoms during pregnancy Hyperemesis Gravidarum Morning sickness Pregnancy and travel Pregnancy and work Problems sleeping during pregnancy Skin and hair changes during pregnancy Teenage pregnancy

Preparing to go home with your baby

Cribs and crib safety Eat right during pregnancy Preparing your other children

Visits and Tests

Amniocentesis Chorionic villus sampling Genetic counseling before pregnancy Glucose tolerance test-pregnancy Monitoring your baby before labor Nuchal translucency Prenatal care in your first trimester Prenatal care in your second trimester Prenatal care in your third trimester

Chromosome

Definition

Chromosomes are structures found in the center (nucleus) of cells that carry long pieces of DNA. DNA is the material that holds genes. It is the building block of the human body.

Chromosomes also contain proteins that help DNA exist in the proper form.

Information

Chromosomes come in pairs. Normally, each cell in the human body has 23 pairs of chromosomes (46 total chromosomes). Half come from the mother; the other half come from the father.

Two of the chromosomes (the X and the Y chromosome) are called sex chromosomes, and in almost all people:

• Females have 2 X chromosomes.

• Males have 1 X and 1 Y chromosome.

At conception, the mother gives an X chromosome to the child, and the father may contribute an X or a Y. The chromosome from the father determines if the baby is female or male. In most cases, a child is born as a male or female according to their chromosomes. However, children with differences of sex development may be born with genitalia that do not match their chromosomes. Or they may have fewer or more than 46 chromosomes. All of these conditions can cause problems with sexual development.

The remaining chromosomes are called autosomal chromosomes. They are known as chromosome pairs 1 through 22.

References

Perle MA, Stein CH. Applications of cytogenetics in modern pathology. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 71.

Taber's Cyclopedic Medical Dictionary. 24th ed. F.A. Davis Company; 2021. www.tabers.com/tabersonline. Accessed June 12, 2023.

Review Date: 4/27/2023

Reviewed By: Linda J. Vorvick, MD, Clinical Professor, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. Editorial update 11/16/2023.